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Health // Tuesday, November 18, 2008 Print Article Email To Friend(s) Feedback Text Larger Text Smaller One Column Two Columns  
Acinetobacter is emerging hospital superbug: study
Time is GMT + 8 hours
Posted: 18-Nov-2008 08:06 hrs
A nurse wears a surgical mask to protect against infection. Health providers must arm themselves against a deadly drug-resistant germ that is becoming increasingly common in hospitals and other settings, a study warned on Tuesday.
 
 
Health providers must arm themselves against a deadly drug-resistant germ that is becoming increasingly common in hospitals and other settings, a study warned on Tuesday.
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Headlines about hospital superbugs have focussed overwhelmingly on bacteria called MRSA, for methicillin-resistant staphylococcus aureus (MRSA).
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But a different pathogen, Acinetobacter baumannii, is an expanding threat and controlling outbreaks of it are proving extremely difficult, said the study, published in the British medical journal The Lancet.
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Nearly a third of cases involving infection by A. baumannii have shown resistance to frontline antibiotics, it said, citing research data.
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"Institutional outbreaks caused by multidrug resistant strains are a growing public health problem," said co-authors Drosos Karageorgopoulos and Matthew Falagas of the Alfa Institute of Biomedical Sciences in Athens.
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According to a 2004 study of 24,000 US cases, 34 percent of patients whose bloodstream became infected by A. baumannii while in hospital eventually died, a figure that rose to 43 percent among those in intensive care, they said.
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Urgent measures must be taken to prevent outbreaks in healthcare facilities, and to identify which drugs and drug combinations are the most effective in neutralising the bacteria, they warned.
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A. baumannii rarely attacks healthy individuals, and is more frequently found among critically ill hospital patients.
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Conditions which favor the superbug are advanced age, serious underlying diseases, weakened immune systems, along with major trauma and burns.
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Patients who have undergone surgery or are fitted with catheters are also more vulnerable to infection, along with persons breathing with the help of mechanical ventilation.
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Symptoms include pneumonia and bacteria in the blood, as well as infection of surgical sites and the urinary tract.
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The new study reviews different options for controlling and treating infections.
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Stricter hygiene practices -- sterilisation of reusable medical equipment, hand washing, limiting physical contact -- are essential, the researchers say.
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They also review the panoply of antibiotics available.
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Long regarded as the "agents of choice," a category of treatment called carbapenems has shown much higher rates of resistance in recent years.
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Other antibiotic groups -- polymyxins and minocyclines -- have been shown to be more effective. — AFP

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